The Cytokeratin 19 Rabbit Monoclonal Antibody (CAB19040) is a high-quality research tool specifically designed for detecting Cytokeratin 19, a protein marker used in the identification and classification of various cancers, including breast, lung, and colorectal cancers. This monoclonal antibody is raised in rabbits and has been validated for use in immunohistochemistry applications.Cytokeratin 19 is a member of the cytokeratin family of proteins, which are essential components of the cytoskeleton and play a critical role in maintaining cell structure and integrity.
Elevated levels of Cytokeratin 19 have been observed in a variety of cancer types, making it a valuable biomarker for cancer diagnosis and prognosis.The Cytokeratin 19 Rabbit Monoclonal Antibody (CAB19040) provides researchers with a reliable tool for studying the expression and distribution of Cytokeratin 19 in tissue samples, aiding in the understanding of cancer development and progression. Its high specificity and sensitivity make it an ideal choice for researchers in the fields of oncology and pathology.
Product Name:
Cytokeratin 19 (KRT19) Rabbit Monoclonal Antibody
SKU:
CAB19040
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 19 (KRT19) (KRT19) (P08727).
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Purification Method:
Affinity purification
Gene ID:
3880
Clone Number:
ARC2811
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Cytokeratin 19 (CK19) Rabbit mAb (CAB19040) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC): HeLaExposure time: 0.5s.
