The Cytokeratin 14 Rabbit Monoclonal Antibody (CAB19039) is a valuable tool for research involving the detection and analysis of Cytokeratin 14 (CK14) protein expression. CK14 is a member of the cytoskeletal intermediate filament protein family, specifically expressed in epithelial cells. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in immunohistochemistry and Western blot applications.CK14 serves as a marker for various epithelial cell types and is commonly used in studies related to tissue development, wound healing, and cancer research.
Its expression patterns provide valuable insights into cell differentiation and epithelial cell function, making this antibody an essential component for researchers in the fields of cell biology, oncology, and regenerative medicine.By utilizing the Cytokeratin 14 Rabbit Monoclonal Antibody, researchers can accurately detect and quantify CK14 expression, allowing for detailed analysis of epithelial cell populations in a wide range of experimental settings. This antibody is an invaluable tool for advancing our understanding of epithelial biology and its implications in disease progression and treatment strategies.
Product Name:
Cytokeratin 14 (KRT14) Rabbit Monoclonal Antibody
SKU:
CAB19039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 264-457 of human Cytokeratin 14 (KRT14) (P02533).
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Purification Method:
Affinity purification
Gene ID:
3861
Clone Number:
ARC0351
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from SK-OV-3 cells, using Cytokeratin 14 (KRT14) Rabbit mAb (CAB19039) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
