The Cytochrome B5 Polyclonal Antibody (CAB5401) is a valuable tool for researchers studying cytochrome B5, a heme-binding protein involved in electron transfer in various metabolic pathways. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.Cytochrome B5 is a crucial component of the electron transport chain in cells, playing a key role in metabolic processes such as drug metabolism, fatty acid desaturation, and steroid biosynthesis. Dysregulation of cytochrome B5 has been linked to various diseases, including metabolic disorders and cancer.
Therefore, studying the expression and function of cytochrome B5 is essential for understanding its role in health and disease.With its high reactivity and specificity for human samples, the Cytochrome B5 Polyclonal Antibody enables researchers to detect and analyze cytochrome B5 in various cell types, making it an ideal tool for studies in biochemistry, metabolism, and cancer research. By gaining insights into the function of cytochrome B5, researchers can uncover new therapeutic targets and strategies for treating diseases associated with cytochrome B5 dysregulation.
Product Name:
CYB5A Rabbit Polyclonal Antibody
SKU:
CAB5401
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CYB5A (NP_683725.1).
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1528
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CYB5A Rabbit pAb (CAB5401) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
