The CYTH1 Polyclonal Antibody (CAB15351) is a valuable tool for researchers studying CYTH1, a protein involved in cellular signaling and membrane trafficking processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CYTH1 protein, this antibody enables the detection and analysis of CYTH1 in various cell types.CYTH1, also known as Cytohesin-1, plays a crucial role in regulating vesicular trafficking and intracellular signaling pathways. Dysregulation of CYTH1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
Therefore, investigating the function of CYTH1 is essential for understanding its role in disease pathogenesis and developing targeted therapies.Overall, the CYTH1 Polyclonal Antibody (CAB15351) serves as a valuable tool for researchers interested in studying the functions and mechanisms of CYTH1 in cellular processes and disease contexts. Its high specificity and reactivity make it an ideal choice for immunology, cell biology, and cancer research studies.
Product Name:
CYTH1 Rabbit Polyclonal Antibody
SKU:
CAB15351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH1 (NP_004753.1).
Sequence:
MEED DSYV PSDL TAEE RQEL ENIR RRKQ ELLA DIQR LKDE IAEV ANEI ENLG STEE RKNM QRNK QVAM GR
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CYTH1 Rabbit pAb (CAB15351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
