CYTH1 Rabbit Polyclonal Antibody (CAB15351)
- SKU:
- CAB15351
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CYTH1 Rabbit Polyclonal Antibody |
SKU: | CAB15351 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH1 (NP_004753.1). |
Sequence: | MEED DSYV PSDL TAEE RQEL ENIR RRKQ ELLA DIQR LKDE IAEV ANEI ENLG STEE RKNM QRNK QVAM GR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | B2-1; SEC7; PSCD1; D17S811E; CYTOHESIN-1; CYTH1 |
Positive Sample: | Raji,Mouse brain,Mouse heart,Mouse spleen,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Peripheral membrane protein, cytosol. |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9267 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |