CST6 Rabbit Polyclonal Antibody (CAB8115)
- SKU:
- CAB8115
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | CST6 Rabbit Polyclonal Antibody |
SKU: | CAB8115 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-149 of human CST6 (NP_001314.1). |
Sequence: | RPQE RMVG ELRD LSPD DPQV QKAA QAAV ASYN MGSN SIYY FRDT HIIK AQSQ LVAG IKYF LTME MGST DCRK TRVT GDHV DLTT CPLA AGAQ QEKL RCDF EVLV VPWQ NSSQ LLKH NCVQ M |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ECTD15; CST6 |
Positive Sample: | 293T,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 17kDa |
Observed MW: | 15kDa |
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
Purification Method: | Affinity purification |
Gene ID: | 1474 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |