The Cystathionase Rabbit Monoclonal Antibody (CAB5101) is a valuable tool for researchers studying cystathionase, an enzyme involved in the metabolism of the amino acid methionine. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting cystathionase in human samples through Western blot applications.Cystathionase plays a key role in the transsulfuration pathway, converting cystathionine into cysteine and alpha-ketobutyrate. Dysregulation of this pathway has been implicated in various diseases, including cardiovascular diseases and certain types of cancer.
By targeting cystathionase with this monoclonal antibody, researchers can gain insights into the functions and dysregulation of this enzyme in different cellular contexts.With its ability to detect and analyze cystathionase in various cell types, this antibody is an essential tool for scientific studies in biochemistry, metabolism, and disease research. By understanding the role of cystathionase, researchers may uncover potential therapeutic targets and develop new treatments for diseases associated with abnormalities in methionine metabolism.
Product Name:
Cystathionase/CTH Rabbit Monoclonal Antibody
SKU:
CAB5101
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cystathionase/CTH (P32929).
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
1491
Clone Number:
ARC1200
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cystathionase/CTH Rabbit mAb (CAB5101) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
