The CysLT2 Polyclonal Antibody (CAB16556) is a valuable tool for researchers studying CysLT2, a cell surface receptor involved in inflammatory responses and allergic reactions. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples, making it an ideal choice for Western blot applications. By binding to the CysLT2 protein, researchers can accurately detect and analyze its expression in various cell types, providing insights into its role in immunology and inflammation.CysLT2 is known for its ability to mediate inflammatory processes and contribute to the pathogenesis of conditions such as asthma, allergic rhinitis, and inflammatory bowel disease.
Targeting CysLT2 with specific antibodies like CAB16556 is crucial for investigating its molecular mechanisms and potential therapeutic implications in these disease contexts. By understanding the function of CysLT2, researchers can develop novel strategies for managing inflammatory and allergic conditions, ultimately improving patient outcomes.
Product Name:
CYSLTR2 Rabbit Polyclonal Antibody
SKU:
CAB16556
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human CYSLTR2 (NP_001295394.1).
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.
Purification Method:
Affinity purification
Gene ID:
57105
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using CYSLTR2 Rabbit pAb (CAB16556) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
