CYSLTR1 Rabbit Polyclonal Antibody (CAB1815)
- SKU:
- CAB1815
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | CYSLTR1 Rabbit Polyclonal Antibody |
SKU: | CAB1815 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CYSLTR1 (NP_006630.1). |
Sequence: | MDET GNLT VSSA TCHD TIDD FRNQ VYST LYSM ISVV GFFG NGFV LYVL IKTY HKKS AFQV YMIN LAVA DLLC VCTL PLRV VYYV HKGI WLFG DFLC RLST |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CYSLT1; CYSLTR; CYSLT1R; HMTMF81; CYSLTR1 |
Positive Sample: | U-937,A-549,BxPC-3,HeLa,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 39kDa |
Observed MW: | 38kDa |
This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10800 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |