The CYR61 Polyclonal Antibody (CAB1111) is a valuable tool for researchers studying the role of CYR61, a secreted extracellular matrix-associated protein that plays a key role in cell adhesion, migration, and angiogenesis. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for detecting CYR61 in human samples, making it ideal for use in Western blot and immunohistochemistry applications.CYR61, also known as cysteine-rich protein 61, is involved in various physiological processes, including wound healing, tissue regeneration, and cancer progression. Its dysregulation has been implicated in the pathogenesis of multiple diseases, making it a promising target for therapeutic interventions.
By using the CYR61 Polyclonal Antibody, researchers can gain insight into the mechanisms underlying CYR61-mediated signaling pathways and their potential contribution to disease development.Overall, the CYR61 Polyclonal Antibody is a valuable resource for researchers interested in unraveling the biological functions of CYR61 and exploring its therapeutic potential in a variety of pathological conditions. Its high specificity and sensitivity make it a reliable tool for studying CYR61 expression and function in different cell types and tissues, advancing our understanding of the molecular mechanisms underlying disease progression.
Product Name:
CYR61 Rabbit Polyclonal Antibody
SKU:
CAB1111
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 120-220 of human CYR61 (NP_001545.2).
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.
Purification Method:
Affinity purification
Gene ID:
3491
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CYR61 antibody (CAB1111) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
