CYP51A1 Polyclonal Antibody (CAB6252)
- SKU:
- CAB6252
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP51A1 Polyclonal Antibody |
SKU: | CAB6252 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of CYP51A1 (NP_000777.1). |
Sequence: | LTAS HCLH GKEI RSQL NEKV AQLY ADLD GGFS HAAW LLPG WLPL PSFR RRDR AHRE IKDI FYKA IQKR RQSQ EKID DILQ TLLD ATYK DGRP LTDD EVAG MLIG LLLA GQHT SSTT SAWM GFFL ARDK TLQK KCYL EQKT VCGE NLPP LTYD QLKD LNLL DRCI KETL RLRP PIMI MMRM ARTP QTVA GYTI PPGH QVCV SPTV NQRL KDSW VERL DFNP DRYL QDNP ASGE KFAY VPFG AGRH RCIG ENFA YVQI KTIW STML RLYE FDLI DGYF PTVN YTTM IHTP ENPV IRYK RRSK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM; CYP51A1 |
Positive Sample: | Mouse liver,Mouse testis,Rat liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1595 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |