CYP51A1 Rabbit Polyclonal Antibody (CAB13485)
- SKU:
- CAB13485
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP51A1 Rabbit Polyclonal Antibody |
SKU: | CAB13485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-420 of CYP51A1 (NP_000777.1). |
Sequence: | WLLP GWLP LPSF RRRD RAHR EIKD IFYK AIQK RRQS QEKI DDIL QTLL DATY KDGR PLTD DEVA GMLI GLLL AGQH TSST TSAW MGFF LARD KTLQ KKCY LEQK TVCG ENLP PLTY DQLK DLNL LDRC IKET LRLR PPIM IMMR MART PQTV AGYT IPPG HQVC VSPT VNQR LKDS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM; CYP51A1 |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane. |
Calculated MW: | 57kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1595 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |