The CYP4Z1 Polyclonal Antibody (PAC003605) is a valuable tool for researchers studying the cytochrome P450 family member 4Z1 (CYP4Z1), an enzyme involved in the metabolism of various compounds including drugs and fatty acids. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the CYP4Z1 protein, this antibody allows for accurate detection and analysis in different cell types, making it ideal for investigations in pharmacology and drug metabolism research.
CYP4Z1 plays a crucial role in the enzymatic breakdown of endogenous and exogenous substrates, making it a target of interest in understanding drug metabolism and bioactivation processes. Its involvement in the metabolism of lipids and fatty acids also suggests potential implications in lipid homeostasis and related metabolic disorders. By elucidating the function and regulation of CYP4Z1, researchers can gain insights into its impact on drug efficacy, toxicity, and disease susceptibility, paving the way for advancements in personalized medicine and pharmacogenomics.
Antibody Name:
CYP4Z1 Antibody
Antibody SKU:
PACO03605
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human CYP4Z1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CYP4Z1; Cytochrome P450 4Z1; CYPIVZ1
UniProt Protein Function:
CYP4Z1: a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]Protein type: EC 1.14.14.1; Membrane protein, integral; OxidoreductaseChromosomal Location of Human Ortholog: 1p33
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]
