The CYP4X1 Polyclonal Antibody (CAB17848) is a valuable tool for research involving the CYP4X1 enzyme, a member of the cytochrome P450 family involved in the metabolism of various compounds, including drugs and hormones. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CYP4X1 enzyme, this antibody enables detection and analysis in a wide range of cell types, making it ideal for studies in drug metabolism, toxicology, and hormone regulation.CYP4X1 is a key player in the body's metabolic processes, particularly in the breakdown of foreign substances and the regulation of endogenous compounds.
Its role in drug metabolism makes it a target of interest in pharmacology and toxicology research, and its involvement in hormone regulation may have implications for endocrine disorders and hormone-related diseases. By studying the activity of CYP4X1, researchers can gain valuable insights into how the body processes and responds to various substances, leading to advancements in personalized medicine and drug development.
Product Name:
CYP4X1 Rabbit Polyclonal Antibody
SKU:
CAB17848
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-290 of human CYP4X1 (NP_828847.1).
This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
260293
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using CYP4X1 Rabbit pAb (CAB17848) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
