The CYP4F22 Polyclonal Antibody (PAC055174) is a valuable tool for researchers studying the cytochrome P450 4F22 enzyme, which is involved in the metabolism of fatty acids and lipid signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.The CYP4F22 enzyme plays a crucial role in lipid metabolism, specifically in the oxidation of fatty acids, which is important for maintaining lipid homeostasis in the body.
Dysregulation of CYP4F22 activity has been linked to various diseases, including skin disorders and metabolic disorders.By using the CYP4F22 Polyclonal Antibody, researchers can detect and analyze the expression of the CYP4F22 enzyme in different cell types, providing valuable insights into its function and potential therapeutic applications. This antibody is an essential tool for investigations in the fields of lipid metabolism, skin biology, and metabolic diseases.
Antibody Name:
CYP4F22 Antibody (PACO55174)
Antibody SKU:
PACO55174
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Cytochrome P450 4F22 protein (413-507AA)
Western Blot. Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate. All lanes: CYP4F22 antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 62 kDa. Observed band size: 62 kDa.
Background:
endoplasmic reticulum membrane, monooxygenase activity, icosanoid metabolic process
Synonyms:
Cytochrome P450 4F22 (EC 1.14.14), CYP4F22
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008]
