The CYP4F2 Polyclonal Antibody (CAB10128) is a valuable tool for researchers studying the cytochrome P450 4F2 enzyme, which plays a critical role in the metabolism of fatty acids and eicosanoids. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the CYP4F2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in the fields of drug metabolism, lipid metabolism, and cardiovascular health.
CYP4F2 is a key enzyme involved in the biosynthesis of omega-3 and omega-6 fatty acids, as well as the regulation of inflammation and blood pressure. Dysregulation of CYP4F2 activity has been implicated in various health conditions, including cardiovascular diseases, metabolic disorders, and inflammatory conditions. By gaining insight into the function of CYP4F2, researchers can explore new therapeutic strategies for treating these diseases and improving overall patient health.
Product Name:
CYP4F2 Rabbit Polyclonal Antibody
SKU:
CAB10128
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-120 of human CYP4F2 (NP_001073.3).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.
Purification Method:
Affinity purification
Gene ID:
8529
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CYP4F2 antibody (CAB10128) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
