The CYP4F11 Polyclonal Antibody is a powerful tool for researchers studying cytochrome P450 family 4 subfamily F member 11 (CYP4F11), an enzyme involved in the metabolism of various endogenous compounds and xenobiotics. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It targets the CYP4F11 protein, allowing for precise detection and analysis in a range of cell types, making it well-suited for investigations in pharmacology and toxicology.CYP4F11 is known for its role in the oxidation of fatty acids and its potential involvement in drug metabolism and detoxification processes.
Understanding the function and regulation of CYP4F11 is crucial for developing safer and more effective therapeutic interventions in the fields of drug development and toxicology. The CYP4F11 Polyclonal Antibody provides researchers with a reliable tool to explore the expression and activity of this important enzyme, aiding in the advancement of drug discovery and personalized medicine.
Product Name:
CYP4F11 Polyclonal Antibody
SKU:
CAB20682
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-130 of human CYP4F11 (NP_001122404.1).
Sequence:
FWGH QGLV TPTE EGMK TLTQ LVTT YPQG FKLW LGPT FPLL ILCH PDII RPIT SASA AVAP KDMI FYGF LKP
Tested Applications:
IF/ICCELISA
Recommended Dilution:
IF/ICC,1:50 - 1:200
Synonyms:
CYPIVF11; CYP4F11
Conjugate:
Unconjugated
Calculated MW:
60kDa
Observed MW:
Refer to figures
This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57834
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of A-549 cells using CYP4F11 Rabbit pAb (CAB20682) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
