The CYP39A1 Polyclonal Antibody is a high-quality research tool specifically designed for studying the CYP39A1 protein, which plays a key role in steroid hormone metabolism. This antibody is produced in rabbits and has been validated for use in various applications, including Western blotting. By binding to the CYP39A1 protein, researchers can accurately detect and analyze its expression in different sample types.CYP39A1 is a crucial enzyme involved in the conversion of cholesterol into bile acids, making it essential for lipid metabolism and overall physiological processes.
Dysregulation of CYP39A1 has been linked to various diseases, including metabolic disorders and liver diseases. Therefore, studying the expression and function of CYP39A1 using this polyclonal antibody can provide valuable insights into related pathologies and potential therapeutic targets.Overall, the CYP39A1 Polyclonal Antibody is a reliable tool for researchers studying steroid hormone metabolism, lipid metabolism, and related diseases. Its specificity and sensitivity make it ideal for use in immunology, oncology, and metabolic research studies.
Product Name:
CYP39A1 Polyclonal Antibody
SKU:
CAB23146
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthesized peptide derived from human CYP39A1.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:5000
Positive Sample:
Mouse liver,Rat liver
Conjugate:
Unconjugated
Calculated MW:
54kDa
Observed MW:
54kDa
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51302
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CYP39A1 Rabbit pAb (CAB23146) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
