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CYP2S1 Antibody (PACO08717)

SKU:
PACO08717
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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CYP2S1 Antibody (PACO08717)

The CYP2S1 Polyclonal Antibody (PACO08717) is a powerful tool for researchers studying the cytochrome P450 2S1 enzyme, which plays a key role in the metabolism of various compounds in the body. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CYP2S1 enzyme, researchers can accurately detect and analyze its expression in a variety of cell types, making it an essential tool for studies in drug metabolism, toxicology, and cancer research.

The CYP2S1 enzyme is involved in the metabolism of endogenous and exogenous compounds, including drugs, carcinogens, and environmental toxins. Understanding the function and regulation of CYP2S1 is crucial for elucidating its role in drug metabolism and metabolic activation of procarcinogens. Research into the activity of CYP2S1 may lead to the development of novel therapeutic strategies for cancer treatment and drug development.

Antibody Name:CYP2S1 Antibody (PACO08717)
Antibody SKU:PACO08717
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human CYP2S1
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:cytochrome P450, family 2, subfamily S, polypeptide 1;
UniProt Protein Function:CYP2S1: Has a potential importance for extrahepatic xenobiotic metabolism. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 1.14.14.1; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm

Molecular Function:iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding

Biological Process: xenobiotic metabolic process; exogenous drug catabolic process; epoxygenase P450 pathway

NCBI Summary:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q96SQ9
NCBI GenInfo Identifier:48428134
NCBI Gene ID:29785
NCBI Accession:Q96SQ9.2
UniProt Secondary Accession:Q96SQ9,Q9BZ66,
UniProt Related Accession:Q96SQ9
Molecular Weight:504
NCBI Full Name:Cytochrome P450 2S1
NCBI Synonym Full Names:cytochrome P450, family 2, subfamily S, polypeptide 1
NCBI Official Symbol:CYP2S1  
NCBI Official Synonym Symbols:CYPIIS1  
NCBI Protein Information:cytochrome P450 2S1; cytochrome P540, subfamily IIS, polypeptide 1
UniProt Protein Name:Cytochrome P450 2S1
UniProt Synonym Protein Names:CYPIIS1
Protein Family:Cytochrome
UniProt Gene Name:CYP2S1  
UniProt Entry Name:CP2S1_HUMAN

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