The CYP2J2 Polyclonal Antibody (CAB5805) is a valuable tool for researchers studying the CYP2J2 enzyme, which plays a key role in metabolism and detoxification processes in the body. This antibody is produced in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications.CYP2J2 is a member of the cytochrome P450 enzyme family and is primarily expressed in the liver and cardiovascular system. It is involved in the metabolism of various endogenous compounds, as well as in the activation and detoxification of exogenous chemicals.
Research on CYP2J2 is important for understanding its role in drug metabolism, cardiovascular health, and other physiological processes.By using the CYP2J2 Polyclonal Antibody, researchers can detect and analyze the CYP2J2 protein in different cell types, providing insights into its function and regulation. This antibody is a valuable tool for studies in pharmacology, toxicology, and personalized medicine, where understanding CYP2J2 activity can help guide drug development and treatment strategies.
Product Name:
CYP2J2 Rabbit Polyclonal Antibody
SKU:
CAB5805
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 221-320 of human CYP2J2 (NP_000766.2).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1573
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CYP2J2 Antibody (CAB5805) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
