The Cytochrome P450 2F1 Polyclonal Antibody (CAB7550) is a powerful tool for researchers studying the Cytochrome P450 2F1 enzyme, an important member of the cytochrome P450 superfamily involved in drug metabolism and detoxification processes in the liver.This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting Cytochrome P450 2F1 in human samples, making it an essential tool for Western blot applications. By specifically binding to the Cytochrome P450 2F1 protein, this antibody enables accurate detection and analysis in various cell types, facilitating research in pharmacology, toxicology, and drug development.The Cytochrome P450 2F1 enzyme plays a crucial role in metabolizing a wide range of drugs, environmental toxins, and endogenous compounds, influencing drug efficacy and toxicity in individuals.
Understanding the function and regulation of Cytochrome P450 2F1 is essential for predicting drug-drug interactions, optimizing drug therapies, and developing personalized medicine approaches.Researchers studying drug metabolism, pharmacokinetics, and liver function will benefit from using the Cytochrome P450 2F1 Polyclonal Antibody (CAB7550) to explore the role of this enzyme in health and disease. Its reliability and accuracy make it an indispensable tool for advancing research in pharmacology and toxicology fields.
Product Name:
CYP2F1 Rabbit Polyclonal Antibody
SKU:
CAB7550
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-290 of human CYP2F1 (NP_000765.2).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Purification Method:
Affinity purification
Gene ID:
1572
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CYP2F1 Rabbit pAb (CAB7550) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
