CYP2C18 Rabbit Polyclonal Antibody (CAB7431)
- SKU:
- CAB7431
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CYP2C18 Rabbit Polyclonal Antibody |
SKU: | CAB7431 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 231-490 of human CYP2C18 (NP_000763.1). |
Sequence: | NKIA ENFA YIKS YVLE RIKE HQES LDMN SARD FIDC FLIK MEQE KHNQ QSEF TVES LIAT VTDM FGAG TETT STTL RYGL LLLL KYPE VTAK VQEE IECV VGRN RSPC MQDR SHMP YTDA VVHE IQRY IDLL PTNL PHAV TCDV KFKN YLIP KGTT IITS LTSV LHND KEFP NPEM FDPG HFLD KSGN FKKS DYFM PFSA GKRM CMGE GLAR MELF LFLT TILQ NFNL KSQV DPKD IDIT PIAN AFGR VPPL YQLC FIPV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CPCI; CYP2C; CYP2C17; P450IIC17; P450-6B/29C; CYP2C18 |
Positive Sample: | Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. |
Calculated MW: | 56kDa |
Observed MW: | 50kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1562 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |