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CYP2A13 Antibody

SKU:
PACO64657
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Applications:
ELISA
WB
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

CYP2A13 Antibody (PACO64657)

The CYP2A13 Polyclonal Antibody (PACO64657) is a valuable tool for researchers studying the CYP2A13 enzyme, which is involved in the metabolism of various compounds, including nicotine and certain carcinogens. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CYP2A13 is a member of the cytochrome P450 superfamily of enzymes, which play a crucial role in the detoxification and activation of xenobiotics in the body. This particular enzyme is predominantly expressed in the respiratory tract and is known to be involved in the bioactivation of tobacco-specific nitrosamines, making it a potential target for studying the link between tobacco smoking and lung cancer.

By utilizing the CYP2A13 Polyclonal Antibody, researchers can detect and analyze the expression of the CYP2A13 enzyme in various cell types and tissues, enabling further exploration into its role in chemical metabolism and its potential implications for human health. This antibody is essential for investigations in toxicology, pharmacology, and cancer research, providing valuable insights into the mechanisms underlying drug metabolism and chemical carcinogenesis.

Product Name:CYP2A13 Antibody
Product Code:PACO64657
Size:50µL
Target Names:CYP2A13
Species Reactivity:Human, Mouse
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:100-1:500
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Recombinant Human Cytochrome P450 2A13 protein (252-354aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Cytochrome P450 2A13 (EC 1.14.14.1) (CYPIIA13), CYP2A13
Uniprot ID:Q16696
Background:Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity.
Research Area:Cardiovascular

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