CYP27A1 Rabbit Polyclonal Antibody (CAB1982)
- SKU:
- CAB1982
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP27A1 Rabbit Polyclonal Antibody |
SKU: | CAB1982 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human CYP27A1 (NP_000775.1). |
Sequence: | NQVS DMAQ LFYY FALE AICY ILFE KRIG CLQR SIPE DTVT FVRS IGLM FQNS LYAT FLPK WTRP VLPF WKRY LDGW NAIF SFGK KLID EKLE DMEA QLQA AGPD GIQV SGYL HFLL ASGQ LSPR EAMG SLPE LLMA GVDT TSNT LTWA LYHL SKDP EIQE ALHE EVVG VVPA GQVP QHKD FAHM PLLK AVLK ETLR LYPV V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CTX; CP27; CYP27; CYP27A1 |
Positive Sample: | 293T,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.
Purification Method: | Affinity purification |
Gene ID: | 1593 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |