The CYP26B1 Polyclonal Antibody (PAC061398) is a valuable tool for research involving CYP26B1, a cytochrome P450 enzyme that plays a key role in the metabolism of retinoic acid. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CYP26B1 protein, this antibody allows for the detection and analysis of CYP26B1 in various cell types, making it an ideal choice for studies in pharmacology, toxicology, and developmental biology.
CYP26B1 is essential for the regulation of retinoic acid levels in the body, which in turn impacts processes such as cell growth, differentiation, and gene expression. Dysregulation of CYP26B1 has been linked to developmental disorders, as well as diseases like cancer and metabolic disorders. By investigating the function and activity of CYP26B1, researchers can gain insights into these conditions and potentially develop novel treatment strategies targeting this enzyme.
Antibody Name:
cyp26b1 Antibody (PACO61398)
Antibody SKU:
PACO61398
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Zebrafish
Immunogen:
Recombinant Zebrafish Cytochrome P450 26B1 protein (366-511AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: cyp26b1 antibody at 4.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 46 kDa. Observed band size: 51 kDa.
Background:
Involved in the metabolism of retinoic acid, (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid, (RA). Plays a role in skeletal development.
Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid (RA). Plays a role in skeletal development.
