CYP26B1 Rabbit Polyclonal Antibody (CAB12142)
- SKU:
- CAB12142
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CYP26B1 Rabbit Polyclonal Antibody |
SKU: | CAB12142 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 213-512 of human CYP26B1 (NP_063938.1). |
Sequence: | VYQQ FVDN VFSL PVDL PFSG YRRG IQAR QILQ KGLE KAIR EKLQ CTQG KDYL DALD LLIE SSKE HGKE MTMQ ELKD GTLE LIFA AYAT TASA STSL IMQL LKHP TVLE KLRD ELRA HGIL HSGG CPCE GTLR LDTL SGLR YLDC VIKE VMRL FTPI SGGY RTVL QTFE LDGF QIPK GWSV MYSI RDTH DTAP VFKD VNVF DPDR FSQA RSED KDGR FHYL PFGG GVRT CLGK HLAK LFLK VLAV ELAS TSRF ELAT RTFP RITL VPVL HPVD GLSV KFFG LDSN QNEI LPET EAML SATV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RHFCA; CYP26A2; P450RAI2; P450RAI-2; CYP26B1 |
Positive Sample: | MCF7,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. |
Calculated MW: | 58kDa |
Observed MW: | 58-65kDa |
This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 56603 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |