CYP24A1 Rabbit Polyclonal Antibody (CAB1805)
- SKU:
- CAB1805
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CYP24A1 Rabbit Polyclonal Antibody |
SKU: | CAB1805 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-448 of human CYP24A1 (NP_001122387.1). |
Sequence: | PQPR EVPV CPLT AGGE TQNA AALP GPTS WPLL GSLL QILW KGGL KKQH DTLV EYHK KYGK IFRM KLGS FESV HLGS PCLL EALY RTES AYPQ RLEI KPWK AYRD YRKE GYGL LILE GEDW QRVR SAFQ KKLM KPGE VMKL DNKI NEVL ADFM GRID ELCD ERGH VEDL YSEL NKWS FESI CLVL YEKR FGLL QKNA GDEA VNFI MAIK TMMS TFGR MMVT PVEL HKSL NTKV WQDH TLAW DTIF KSVK ACID NRLE KYSQ QPSA DFLC DIYH QNRL SKKE LYAA VTEL QLAA VETT ANSL MWIL YNLS RNPQ VQQK LLKE IQSV LPEN QVPR AEDL RNMP YLKA CLKE SMRL TPSV PFTT RTLD KATV LGEY ALPK GIVR KYDI QATD NEPV EMLH SGTL VPSR ELPI AFCQ R |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | CP24; HCAI; CYP24; HCINF1; P450-CC24; CYP24A1 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 59kDa |
Observed MW: | 65kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1591 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |