CYP1B1 Rabbit Polyclonal Antibody (CAB13967)
- SKU:
- CAB13967
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP1B1 Rabbit Polyclonal Antibody |
SKU: | CAB13967 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-543 of human CYP1B1 (NP_000095.2). |
Sequence: | MPWL QYFP NPVR TVFR EFEQ LNRN FSNF ILDK FLRH CESL RPGA APRD MMDA FILS AEKK AAGD SHGG GARL DLEN VPAT ITDI FGAS QDTL STAL QWLL LLFT RYPD VQTR VQAE LDQV VGRD RLPC MGDQ PNLP YVLA FLYE AMRF SSFV PVTI PHAT TANT SVLG YHIP KDTV VFVN QWSV NHDP LKWP NPEN FDPA RFLD KDGL INKD LTSR VMIF SVGK RRCI GEEL SKMQ LFLF ISIL AHQC DFRA NPNE PAKM NFSY GLTI KPKS FKVN VTLR ESME LLDS AVQN LQAK ETCQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CP1B; ASGD6; GLC3A; CYPIB1; P4501B1; CYP1B1 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion, Peripheral membrane protein. |
Calculated MW: | 61kDa |
Observed MW: | Refer to figures |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Purification Method: | Affinity purification |
Gene ID: | 1545 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |