CYP17A1 Rabbit Monoclonal Antibody (CAB5067)
- SKU:
- CAB5067
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CPT7
- CYP17
- P450C17
- S17AH
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP17A1 Rabbit Monoclonal Antibody |
SKU: | CAB5067 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-220 of human CYP17A1 (P05093). |
Sequence: | TLDI ASNN RKGI AFAD SGAH WQLH RRLA MATF ALFK DGDQ KLEK IICQ EIST LCDM LATH NGQS IDIS FPVF VAVT NVIS LICF NTSY KNGD PELN VIQN YNEG IIDN LSKD SLVD LVPW |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CPT7; CYP17; S17AH; P450C17; CYP17A1 |
Positive Sample: | PC-3,U-87MG,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane. |
Calculated MW: | 57kDa |
Observed MW: | 55kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Purification Method: | Affinity purification |
Gene ID: | 1586 |
Clone Number: | ARC1257 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |