CYP11B2 Rabbit Polyclonal Antibody (CAB1443)
- SKU:
- CAB1443
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP11B2 Rabbit Polyclonal Antibody |
SKU: | CAB1443 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B2 (NP_000489.3). |
Sequence: | TVQL MFMP RSLS RWIS PKVW KEHF EAWD CIFQ YGDN CIQK IYQE LAFN RPQH YTGI VAEL LLKA ELSL EAIK ANSM ELTA GSVD TTAF PLLM TLFE LARN PDVQ QILR QESL AAAA SISE HPQK ATTE LPLL RAAL KETL RLYP VGLF LERV VSSD LVLQ NYHI PAGT LVQV FLYS LGRN AALF PRPE RYNP QRWL DIRG SGRN FHHV PFGF GMRQ CLGR RLAE AEML LLLH HVLK HFLV ETLT QEDI KMVY SFIL RPGT SPLL TFRA IN |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | CPN2; ALDOS; CYP11B; CYP11BL; CYPXIB2; P450C18; P-450C18; P450aldo; CYP11B2 |
Positive Sample: | HepG2,MCF7,293T,Mouse brain,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane. |
Calculated MW: | 58kDa |
Observed MW: | 50kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Purification Method: | Affinity purification |
Gene ID: | 1585 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |