CYP11B1 Rabbit Polyclonal Antibody (CAB7664)
- SKU:
- CAB7664
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP11B1 Rabbit Polyclonal Antibody |
SKU: | CAB7664 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3). |
Sequence: | TVQL MFMP RSLS RWTS PKVW KEHF EAWD CIFQ YGDN CIQK IYQE LAFS RPQQ YTSI VAEL LLNA ELSP DAIK ANSM ELTA GSVD TTVF PLLM TLFE LARN PNVQ QALR QESL AAAA SISE HPQK ATTE LPLL RAAL KETL RLYP VGLF LERV ASSD LVLQ NYHI PAGT LVRV FLYS LGRN PALF PRPE RYNP QRWL DIRG SGRN FYHV PFGF GMRQ CLGR RLAE AEML LLLH HVLK HLQV ETLT QEDI KMVY SFIL RPSM FPLL TFRA IN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FHI; CPN1; CYP11B; P450C11; CYP11B1 |
Positive Sample: | HT-29,293T,Mouse eye |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane. |
Calculated MW: | 58kDa |
Observed MW: | 55kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1584 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |