CYP11A1 Polyclonal Antibody (CAB21757)
- SKU:
- CAB21757
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | CYP11A1 Polyclonal Antibody |
SKU: | CAB21757 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human CYP11A1 (NP_000772.2). |
Sequence: | ISTR SPRP FNEI PSPG DNGW LNLY HFWR ETGT HKVH LHHV QNFQ KYGP IYRE KLGN VESV YVID PEDV ALLF KSEG PNPE RFLI PPWV AYHQ YYQR PIGV LLKK SAAW KKDR VALN QEVM APEA TKNF LPLL DAVS RDFV SVLH RRIK KAGS GNYS GDIS DDLF RFAF ESIT NVIF GERQ GMLE EVVN PEAQ RFID AIYQ MFHT SVPM LNLP PDLF RLFR TKTW KDHV AAWD VIFS KADI YTQN FYWE LRQK GSVH HDYR GILY RLLG DSKM SFED IKAN V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CYP11A; CYPXIA1; P450SCC; CYP11A1 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane. |
Calculated MW: | 60kDa |
Observed MW: | Refer to figures |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Purification Method: | Affinity purification |
Gene ID: | 1583 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |