CYP11A1 Rabbit Polyclonal Antibody (CAB1713)
- SKU:
- CAB1713
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP11A1 Rabbit Polyclonal Antibody |
SKU: | CAB1713 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of CYP11A1 (NP_000772.2). |
Sequence: | MLAK GLPP RSVL VKGC QTFL SAPR EGLG RLRV PTGE GAGI STRS PRPF NEIP SPGD NGWL NLYH FWRE TGTH KVHL HHVQ NFQK YGPI YREK LGNV ESVY |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CYP11A; CYPXIA1; P450SCC; CYP11A1 |
Positive Sample: | HeLa,Mouse testis,Mouse ovary,Mouse kidney,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion membrane. |
Calculated MW: | 60kDa |
Observed MW: | 50kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Purification Method: | Affinity purification |
Gene ID: | 1583 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |