The CYLD Polyclonal Antibody (CAB3821) is a valuable tool for researchers studying the CYLD protein, a key regulator of immune and inflammatory pathways. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By targeting the CYLD protein, this antibody enables the detection and analysis of CYLD expression in various cell types, making it ideal for investigations in immunology and cancer research.CYLD is a deubiquitinating enzyme that plays a crucial role in regulating immune responses and inflammatory signaling pathways. Dysregulation of CYLD has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
By studying the function of CYLD, researchers can gain insight into the mechanisms underlying these diseases and potentially identify novel therapeutic targets.Overall, the CYLD Polyclonal Antibody (CAB3821) offers researchers a powerful tool for investigating the role of CYLD in immune regulation and disease pathogenesis. Its high specificity and versatility make it a valuable asset for studies aiming to elucidate the molecular mechanisms governing immune responses and inflammatory processes.
Product Name:
CYLD Rabbit Polyclonal Antibody
SKU:
CAB3821
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 654-953 of human CYLD (NP_001035877.1).
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
1540
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CYLD Rabbit pAb (CAB3821) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
