CYFIP1 Rabbit Polyclonal Antibody (CAB10291)
- SKU:
- CAB10291
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CYFIP1 Rabbit Polyclonal Antibody |
SKU: | CAB10291 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CYFIP1 (NP_055423.1). |
Sequence: | MAAQ VTLE DALS NVDL LEEL PLPD QQPC IEPP PSSL LYQP NFNT NFED RNAF VTGI ARYI EQAT VHSS MNEM LEEG QEYA VMLY TWRS CSRA IPQV KCNE QPNR VEIY EKTV EVLE PEVT KLMN FMYF QRNA IERF CGEV RRLC HAER RKDF VSEA YLIT LGKF INMF AVLD ELKN MKCS VKND HSAY KRAA QFLR KMAD PQSI QESQ NLSM FLAN HNKI TQSL QQQL EVIS GYEE LLAD IVNL CVDY YENR MYLT PSEK HMLL KVMG FG |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | SHYC; SRA1; SRA-1; P140SRA-1; CYFIP1 |
Positive Sample: | B cells,BT-474,HepG2,HT-1080,Mouse lung,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, lamellipodium, perinuclear region, ruffle, synapse, synaptosome. |
Calculated MW: | 145kDa |
Observed MW: | 145kDa |
This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion.
Purification Method: | Affinity purification |
Gene ID: | 23191 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |