The CYFIP1 Polyclonal Antibody (CAB10291) is a valuable tool for researchers studying CYFIP1, a protein known to play a key role in cellular processes such as cell adhesion, migration, and T cell activation. This antibody is produced in rabbits and has been validated for Western blot applications, showing high reactivity specifically with human samples.CYFIP1, also known as Cytoplasmic FMR1-interacting protein 1, is essential for the function of the WAVE regulatory complex, which regulates actin polymerization and cytoskeletal reorganization. Dysregulation of CYFIP1 has been implicated in various diseases, including neurological disorders, cancer, and immune-related conditions.
By targeting CYFIP1, researchers can gain insights into the mechanisms underlying these diseases and potentially develop new therapeutic strategies.The CYFIP1 Polyclonal Antibody allows for the detection and analysis of CYFIP1 expression in different cell types, making it a valuable tool for studies in molecular biology, cell biology, and biomedical research. With its specificity and sensitivity, this antibody aids in advancing our understanding of the roles of CYFIP1 in health and disease, paving the way for future developments in diagnosis and treatment.
Product Name:
CYFIP1 Rabbit Polyclonal Antibody
SKU:
CAB10291
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CYFIP1 (NP_055423.1).
This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion.
Purification Method:
Affinity purification
Gene ID:
23191
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CYFIP1 Rabbit pAb (CAB10291) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
