[KO Validated] Cytochrome C Rabbit Polyclonal Antibody (CAB13430)
The CYCS Polyclonal Antibody (CAB13430) is a reliable tool for researchers studying cytochrome c, a crucial protein involved in apoptosis, or programmed cell death. This antibody is raised in rabbits and is highly specific to human samples, making it ideal for various research applications, including Western blotting. By binding to cytochrome c, this antibody enables precise detection and analysis in a range of cell types, offering valuable insights into the mechanisms of cell death and survival.Cytochrome c is a key player in the intrinsic pathway of apoptosis, where it is released from mitochondria into the cytoplasm to trigger a series of events leading to cell death.
Dysregulation of this process is implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. As such, studying the function and regulation of cytochrome c is crucial for understanding the pathophysiology of these conditions and developing targeted therapies.The CYCS Polyclonal Antibody (CAB13430) provides researchers with a powerful tool to investigate the role of cytochrome c in health and disease. Its high specificity and sensitivity make it a valuable asset for studies in cell biology, molecular biology, and biomedical research, ultimately contributing to advances in therapeutic strategies for a range of disorders.
Product Name:
[KO Validated] Cytochrome C Rabbit Polyclonal Antibody
SKU:
CAB13430
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human Cytochrome C (NP_061820.1).
Sequence:
MGDV EKGK KIFI MKCS QCHT VEKG GKHK TGPN LHGL FGRK TGQA PGYS YTAA NKNK GIIW GEDT LMEY LENP KKYI PGTK MIFV GIKK KEER ADLI AYLK KATN E
This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
Purification Method:
Affinity purification
Gene ID:
54205
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney using Cytochrome C Rabbit pAb(CAB13430) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
