The Cyclin Y Polyclonal Antibody (CAB17845) is a valuable tool for research involving Cyclin Y, a protein that plays a role in cell cycle regulation and may have implications in cancer development. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications.Cyclin Y is a member of the cyclin family of proteins, which are key regulators of the cell cycle. It has been implicated in promoting cell proliferation and tumor growth, making it a potential target for cancer therapy research. The Cyclin Y Polyclonal Antibody binds specifically to Cyclin Y protein, allowing for accurate detection and analysis in various cell types.
The importance of understanding Cyclin Y function lies in its potential as a therapeutic target for cancer treatment. By studying the role of Cyclin Y in cell cycle progression and tumor development, researchers can gain valuable insights into how to selectively inhibit its activity for cancer therapy purposes. This antibody is a valuable tool for investigating the role of Cyclin Y in cell biology and cancer research.
Product Name:
Cyclin Y Rabbit Polyclonal Antibody
SKU:
CAB17845
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-120 of human CCNY (NP_859049.2).
cytoplasmic cyclin-dependent protein kinase holoenzyme complex, nucleus, plasma membrane
Calculated MW:
39kDa
Observed MW:
39kDa
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).
Purification Method:
Affinity purification
Gene ID:
219771
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cyclin Y Rabbit pAb (CAB17845) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
