The Cyclin G1 Polyclonal Antibody (CAB5292) is a valuable tool for research involving Cyclin G1, a protein involved in cell cycle regulation and proliferation. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot and immunohistochemistry applications.Cyclin G1 is a key regulator of cell cycle checkpoints and has been implicated in various cellular processes such as DNA damage response and apoptosis. Its dysregulation has been linked to cancer development and progression, making it a potential target for cancer therapy.
The Cyclin G1 Polyclonal Antibody enables accurate detection and analysis of Cyclin G1 expression in different cell types, providing valuable insights into its role in cancer biology and other diseases.Researchers studying cell cycle control, cancer biology, and molecular mechanisms underlying tumorigenesis will find the Cyclin G1 Polyclonal Antibody to be a reliable tool for their experiments. Its specificity and sensitivity make it a powerful instrument for investigating the function of Cyclin G1 and its potential as a therapeutic target in cancer treatment.
Product Name:
Cyclin G1 Rabbit Polyclonal Antibody
SKU:
CAB5292
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-295 of human Cyclin G1 (NP_004051.1).
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
900
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cyclin G1 Rabbit pAb (CAB5292) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
