The Cyclin C Polyclonal Antibody (CAB6545) is a valuable tool for researchers studying the role of cyclin C in cell cycle regulation. Cyclin C is an essential protein involved in the control of cell division, specifically in the G1 phase of the cell cycle. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.By binding to cyclin C, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it ideal for studies in cell biology and cancer research.
Cyclin C plays a crucial role in regulating cell growth and proliferation, making it a key target for therapeutic development in cancer treatment.Understanding the mechanisms through which cyclin C influences cell cycle progression is essential for developing targeted therapies that can disrupt aberrant cell growth in cancer cells. With the Cyclin C Polyclonal Antibody, researchers can gain valuable insights into the function of this protein and its potential as a therapeutic target in cancer treatment.
Product Name:
Cyclin C Rabbit Polyclonal Antibody
SKU:
CAB6545
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human Cyclin C (NP_005181.2).
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
892
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cyclin C Rabbit pAb (CAB6545) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
