The Cyclin B1 Polyclonal Antibody is a powerful tool for researchers studying cell cycle regulation and cancer biology. This antibody, raised in rabbits, specifically targets Cyclin B1, a key regulatory protein involved in cell division.Cyclin B1 is essential for the progression of cells through the G2/M phase of the cell cycle, where it forms complexes with cyclin-dependent kinases to drive mitosis. Dysregulation of Cyclin B1 expression has been linked to various types of cancer, making it a potential therapeutic target.
This antibody is highly reactive with human samples and has been validated for use in Western blot applications, enabling researchers to detect and analyze Cyclin B1 levels in various cell types. Its specificity and sensitivity make it an ideal tool for investigating the role of Cyclin B1 in cancer development and progression.Overall, the Cyclin B1 Polyclonal Antibody is a valuable resource for researchers looking to deepen their understanding of cell cycle regulation and its implications for cancer biology.
Product Name:
Cyclin B1 Polyclonal Antibody
SKU:
CAB0381
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-433 of human Cyclin B1 (NP_114172.1).
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary for proper control of the G2/M transition phase of the cell cycle.
Purification Method:
Affinity purification
Gene ID:
891
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using Cyclin B1 Rabbit pAb (CAB0381).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
