The Cyclin A2 Rabbit Monoclonal Antibody (CAB19036) is a versatile tool for researchers studying cell cycle regulation and cancer biology. This antibody, generated in rabbits, specifically targets Cyclin A2, a key regulator of cell cycle progression and division. Validated for use in Western blot applications, this antibody allows for detection and analysis of Cyclin A2 levels in various cell types.Cyclin A2 plays a crucial role in controlling the transition from G1 to S phase during the cell cycle, making it a promising target for understanding the mechanisms underlying uncontrolled cell growth in cancer.
By studying the expression and activity of Cyclin A2, researchers can gain insights into the dysregulation of cell division processes in cancer cells and potentially identify new therapeutic targets.With its high reactivity towards human samples, the Cyclin A2 Rabbit Monoclonal Antibody is an invaluable tool for investigating the role of Cyclin A2 in cancer progression and identifying novel strategies for cancer treatment. Its specificity and reliability make it an essential reagent for studies in oncology and cell biology.
Product Name:
Cyclin A2 Rabbit Monoclonal Antibody
SKU:
CAB19036
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 11-210 of human Cyclin A2 (P20248).
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
CCN1; CCNA; Cyclin A2
Positive Sample:
HeLa,HCT 116,Jurkat,Mouse testis
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
49kDa
Observed MW:
55kDa
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M.
Purification Method:
Affinity purification
Gene ID:
890
Clone Number:
ARC0359
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cyclin A2 Rabbit mAb (CAB19036) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
