The CYC1 Polyclonal Antibody (CAB10449) is a valuable tool for researchers studying the CYC1 protein, which plays a critical role in cellular respiration and energy production. This antibody, derived from rabbits, is highly specific for detecting CYC1 in human samples and is validated for use in Western blot applications. By targeting the CYC1 protein, researchers can analyze its expression and function in various cell types, making it an ideal tool for studies in bioenergetics, metabolism, and mitochondrial dysfunction.
CYC1 is a key subunit of the cytochrome c oxidase complex, the final enzyme in the electron transport chain responsible for generating ATP in mitochondria. Dysregulation of CYC1 has been linked to metabolic disorders, neurodegenerative diseases, and cancer, making it a promising target for therapeutic interventions. Understanding the role of CYC1 in cellular energy production is crucial for developing strategies to treat conditions associated with mitochondrial dysfunction.
Product Name:
CYC1 Rabbit Polyclonal Antibody
SKU:
CAB10449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 85-291 of human CYC1 (NP_001907.2).
This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6.
Purification Method:
Affinity purification
Gene ID:
1537
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CYC1 antibody (CAB10449) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
