The CYBA Polyclonal Antibody (CAB10694) is a valuable tool for researchers studying the CYBA protein, a crucial component of the NADPH oxidase complex involved in the production of reactive oxygen species. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to CYBA, enabling precise detection and analysis in various cell types.CYBA plays a key role in oxidative stress and inflammation, making it a promising target for research in conditions such as cardiovascular disease, neurodegenerative disorders, and inflammatory conditions.
Understanding the function of CYBA and its involvement in disease processes is essential for developing novel therapeutic strategies to combat oxidative damage and inflammation.Overall, the CYBA Polyclonal Antibody (CAB10694) is a reliable tool for researchers investigating the role of CYBA in various physiological and pathological processes, providing valuable insights into potential therapeutic targets for a range of diseases.
Product Name:
CYBA Rabbit Polyclonal Antibody
SKU:
CAB10694
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 126-195 of human CYBA (NP_000092.2).
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
Purification Method:
Affinity purification
Gene ID:
1535
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of RAW264.7, using CYBA antibody (CAB10694) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
