The CXXC1 Polyclonal Antibody (CAB13424) is a versatile tool for researchers studying CXXC1, a critical regulator of gene expression and chromatin remodeling processes. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for detecting CXXC1 protein in various cell types, making it suitable for use in Western blotting and immunohistochemistry applications.CXXC1, also known as CXXC finger protein 1, is involved in maintaining genomic stability and epigenetic regulation by recognizing unmethylated CpG islands in DNA.
Dysregulation of CXXC1 has been linked to various diseases, including cancer and developmental disorders, highlighting its importance in cellular processes. By using the CAB13424 antibody, researchers can gain insights into the function of CXXC1 in biological pathways and disease mechanisms. This antibody is a valuable tool for advancing research in areas such as cancer biology, epigenetics, and developmental biology.
Product Name:
CXXC1 Rabbit Polyclonal Antibody
SKU:
CAB13424
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CXXC1 (NP_001095124.1).
This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development.
Purification Method:
Affinity purification
Gene ID:
30827
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using CXXC1 antibody (CAB13424) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
