The CXCR5 Rabbit Monoclonal Antibody (CAB8950) is a cutting-edge tool designed for research involving CXCR5, a chemokine receptor that plays a crucial role in immune cell migration and positioning within lymphoid tissues. This antibody, generated using rabbit monoclonal technology, exhibits high specificity and sensitivity for CXCR5 in human samples, making it a reliable choice for various immunological studies.CXCR5, also known as CD185, is known to be expressed on B cells, T follicular helper cells, and subsets of T cells, where it regulates their migration towards B cell follicles and germinal centers. Its role in orchestrating immune cell interactions within secondary lymphoid organs makes it a key target for research into autoimmune diseases, infectious diseases, and cancer.
The CXCR5 Rabbit Monoclonal Antibody (CAB8950) is validated for use in applications such as immunohistochemistry, flow cytometry, and Western blotting, offering researchers flexibility in their experimental approaches. By enabling accurate detection and analysis of CXCR5 expression in various cell types and tissues, this antibody facilitates in-depth investigations into the mechanisms underlying immune responses and inflammatory processes. Unlock the potential of CXCR5 research with this high-quality antibody from AssayGenie.
Product Name:
CXCR5 Rabbit Monoclonal Antibody
SKU:
CAB8950
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 273-372 of human CXCR5 (P32302).
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
643
Clone Number:
ARC1363
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CXCR5 Rabbit mAb (CAB8950) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
