CXCR4 Rabbit Monoclonal Antibody (CAB19035)
- SKU:
- CAB19035
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CXCR4 Rabbit Monoclonal Antibody |
SKU: | CAB19035 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 253-352 of human CXCR4 (P61073). |
Sequence: | LPYY IGIS IDSF ILLE IIKQ GCEF ENTV HKWI SITE ALAF FHCC LNPI LYAF LGAK FKTS AQHA LTSV SRGS SLKI LSKG KRGG HSSV STES ESSS FHSS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; WHIMS1; D2S201E; CXCR4 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Early endosome, Late endosome, Lysosome, Multi-pass membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 43kDa |
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 7852 |
Clone Number: | ARC0381 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |