The CXCR4 Rabbit Monoclonal Antibody (CAB19035) is a cutting-edge tool for researchers studying the CXCR4 protein, a key player in immune response and cell migration. This antibody, derived from rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications.CXCR4, a chemokine receptor, is involved in a wide range of biological processes, including cell signaling, adhesion, and migration. Dysregulation of CXCR4 has been linked to various diseases, such as cancer, HIV infection, and inflammatory disorders.
By targeting CXCR4 with this monoclonal antibody, researchers can gain valuable insights into disease mechanisms and potential therapeutic strategies.The CXCR4 Rabbit Monoclonal Antibody is a valuable tool for immunology and cancer research, providing researchers with a reliable way to detect and analyze CXCR4 expression in different cell types. By understanding the role of CXCR4 in immune modulation and cell migration, researchers can pave the way for innovative treatments and interventions in diseases where CXCR4 plays a crucial role.
Product Name:
CXCR4 Rabbit Monoclonal Antibody
SKU:
CAB19035
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 253-352 of human CXCR4 (P61073).
Cell junction, Cell membrane, Early endosome, Late endosome, Lysosome, Multi-pass membrane protein.
Calculated MW:
40kDa
Observed MW:
43kDa
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
7852
Clone Number:
ARC0381
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using CXCR4 Rabbit mAb (CAB19035) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
