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CXCR1 Rabbit Polyclonal Antibody (CAB16386)

SKU:
CAB16386
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 7 Anti-CXCR1 Antibody CAB16386
  • Cell Biology Antibodies 7 Anti-CXCR1 Antibody CAB16386
  • Cell Biology Antibodies 7 Anti-CXCR1 Antibody CAB16386
  • Cell Biology Antibodies 7 Anti-CXCR1 Antibody CAB16386
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CXCR1 Rabbit Polyclonal Antibody
SKU:CAB16386
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1).
Sequence:IFLL CWLP YNLV LLAD TLMR TQVI QESC ERRN NIGR ALDA TEIL GFLH SCLN PIIY AFIG QNFR HGFL KILA MHGL VSKE FLAR HRVT SYTS SSVN VSSN L
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1; CXCR1
Positive Sample:Jurkat,Raji
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Multi-pass membrane protein.
Calculated MW:40kDa
Observed MW:70kDa

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

Purification Method:Affinity purification
Gene ID:3577
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CXCR1 Rabbit pAb (CAB16386) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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