Cxcl5 Antibody (PACO32680)
- SKU:
- PACO32680
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Cxcl5 Antibody (PACO32680)
The CXCL5 Polyclonal Antibody (PAC032680) is a vital tool for studying the chemokine CXCL5, a crucial player in inflammation and immune responses. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in various research applications, including Western blotting. By binding to the CXCL5 protein, this antibody allows for the detection and analysis of CXCL5 expression in different cell types, making it ideal for investigations in immunology and cancer research.CXCL5, also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78), is involved in recruiting neutrophils to sites of inflammation and promoting angiogenesis.
Its role in inflammation and immune cell recruitment makes it a promising target for research into diseases such as cancer, inflammatory conditions, and autoimmune disorders. Understanding the function of CXCL5 is essential for developing targeted therapies that modulate immune responses and control inflammation in these conditions.
| Antibody Name: | Cxcl5 Antibody (PACO32680) |
| Antibody SKU: | PACO32680 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse C-X-C motif chemokine 5 protein (46-117AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: Mouse heart tissue All lanes: Cxcl5 antibody at 2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 15 kDa Observed band size: 15 kDa . |
| Synonyms: | C-X-C motif chemokine 5 (Cytokine LIX) (Small-inducible cytokine B5) [Cleaved into: GCP-2(1-78); GCP-2(9-78)], Cxcl5, Scyb5 |
| UniProt Protein Function: | CXCL6: Chemotactic for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis Cellular Component: extracellular space; extracellular region Molecular Function:chemokine activity; CXCR chemokine receptor binding; cytokine activity Biological Process: G-protein coupled receptor protein signaling pathway; organ regeneration; cytokine production; positive regulation of JAK-STAT cascade; immune response; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; inflammatory response; chemotaxis; regulation of chemokine production; regulation of cell proliferation; leukocyte homeostasis |
| NCBI Summary: | This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013] |
| UniProt Code: | P50228 |
| NCBI GenInfo Identifier: | 408360041 |
| NCBI Gene ID: | 20311 |
| NCBI Accession: | P50228.2 |
| UniProt Secondary Accession: | P50228,Q8K3I3, |
| UniProt Related Accession: | P50228 |
| Molecular Weight: | 14,235 Da |
| NCBI Full Name: | C-X-C motif chemokine 5 |
| NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 5 |
| NCBI Official Symbol: | Cxcl5Â Â |
| NCBI Official Synonym Symbols: | LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-IIÂ Â |
| NCBI Protein Information: | C-X-C motif chemokine 5; cytokine LIX; small-inducible cytokine B5; granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15 |
| UniProt Protein Name: | C-X-C motif chemokine 5 |
| UniProt Synonym Protein Names: | Cytokine LIX; Small-inducible cytokine B5Cleaved into the following 2 chains:GCP-2(1-78); GCP-2(9-78) |
| UniProt Gene Name: | Cxcl5Â Â |
| UniProt Entry Name: | CXCL5_MOUSE |
| ELISA Kits |
| Mouse CXCL5 / ENA-78 ELISA Kit |
| Mouse GCP-2 (Granulocyte Chemotactic Protein 2) CLIA Kit (MOES00310) |
| Mouse C-X-C motif chemokine 5 (Cxcl5) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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